- See Also
-
Links
- “SGLT2 Inhibition Eliminates Senescent Cells and Alleviates Pathological Aging”, Katsuumi et al 2024
- “Identification of Resibufogenin, a Component of Toad Venom, As a Novel Senolytic Compound in Vitro and for Potential Skin Rejuvenation in Male Mice”, Takaya et al 2023
- “Senolytic Effect of High Intensity Interval Exercise on Human Skeletal Muscle”, Jean et al 2023
- “SenMayo: A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways across Tissues”, Saul et al 2022
- “Unity Biotechnology Announces Positive Data in Phase 2 BEHOLD Study of UBX1325 in Patients With Diabetic Macular Edema”, Biotechnology 2022
- “Mitochondrial Dysfunction in Cell Senescence and Aging”, Miwa et al 2022
- “Orally-Active, Clinically-Translatable Senolytics Restore Α-Klotho in Mice and Humans”, Zhu et al 2022
- “Skin Senescence: Mechanisms and Impact on Whole-Body Aging”, Franco et al 2022
- “Restoration of Hippocampal Neural Precursor Function by Ablation of Senescent Cells in the Aging Stem Cell Niche”, Fatt et al 2022
- “Results of a 5-Year n-Of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment”, Hanley et al 2021
- “A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues”, Saul et al 2021
- “Senolytic Vaccination Improves Normal and Pathological Age-Related Phenotypes and Increases Lifespan in Progeroid Mice”, Suda et al 2021
- “The Flavonoid Procyanidin C1 Has Senotherapeutic Activity and Increases Lifespan in Mice”, Xu et al 2021
- “The Metabolic Roots of Senescence: Mechanisms and Opportunities for Intervention”, Wiley & Campisi 2021
- “Strategies for Targeting Senescent Cells in Human Disease”, Gasek et al 2021
- “Fisetin for COVID-19 in Skilled Nursing Facilities: Senolytic Trials in the COVID Era”, Verdoorn et al 2021
- “Senolytics and the Compression of Late-Life Mortality”, Kowald & Kirkwood 2021
- “Procyanidin C1 Is a Natural Agent With Senolytic Activity against Aging and Age-Related Diseases”, Xu et al 2021
- “Oxylipin Biosynthesis Reinforces Cellular Senescence and Allows Detection of Senolysis”, Wiley et al 2021
- “The Quest to Slow Ageing through Drug Discovery”, Partridge et al 2020
- “Senolytic Drugs: from Discovery to Translation”, Kirkland & Tchkonia 2020
- “A Look Back at 2019: Progress Towards the Treatment of Aging As a Medical Condition”, Reason 2019
- “Metformin and Aging: A Review”, Glossmann & Lutz 2019
- “Senolytic Treatment Targets Aberrant P21-Expression to Restore Liver Regeneration in Adult Mice”, Ritschka et al 2019
- “Galactose-Modified Duocarmycin Prodrugs As Senolytics”, Guerrero et al 2019
- “Senolytics Improve Physical Function and Increase Lifespan in Old Age”, Xu et al 2018
- “The Clinical Potential of Senolytic Drugs”, Kirkland et al 2017
- “Targeting Cellular Senescence Prevents Age-Related Bone Loss in Mice”, Farr et al 2017
- “Naturally Occurring P16(Ink4a)-Positive Cells Shorten Healthy Lifespan”, Baker et al 2016
- “The First Non-Invasive Biomarker to Track and Verify Efficacy of Senolytic Drugs”
- “How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Chemotherapeutic Senolytic Drug Candidates”
- “Thoughts on Attending RAADfest 2018 in San Diego”
- “Overhyping the Effects of Hyperbaric Oxygen Treatment on Aging”
- “A Senolytic Treatment Improves Visual Function in a Small Trial for Macular Degeneration”
- “Peter De Keizer on Senolytics”
- “Reversal of Lung Fibrosis in Mouse Model Suggests a Novel Therapeutic Target for Pulmonary Fibrosis”
- Sort By Magic
- Wikipedia
- Miscellaneous
- Bibliography
See Also
Links
“SGLT2 Inhibition Eliminates Senescent Cells and Alleviates Pathological Aging”, Katsuumi et al 2024
SGLT2 inhibition eliminates senescent cells and alleviates pathological aging
“Identification of Resibufogenin, a Component of Toad Venom, As a Novel Senolytic Compound in Vitro and for Potential Skin Rejuvenation in Male Mice”, Takaya et al 2023
“Senolytic Effect of High Intensity Interval Exercise on Human Skeletal Muscle”, Jean et al 2023
Senolytic effect of high intensity interval exercise on human skeletal muscle
“SenMayo: A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways across Tissues”, Saul et al 2022
“Unity Biotechnology Announces Positive Data in Phase 2 BEHOLD Study of UBX1325 in Patients With Diabetic Macular Edema”, Biotechnology 2022
“Mitochondrial Dysfunction in Cell Senescence and Aging”, Miwa et al 2022
“Orally-Active, Clinically-Translatable Senolytics Restore Α-Klotho in Mice and Humans”, Zhu et al 2022
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
“Skin Senescence: Mechanisms and Impact on Whole-Body Aging”, Franco et al 2022
“Restoration of Hippocampal Neural Precursor Function by Ablation of Senescent Cells in the Aging Stem Cell Niche”, Fatt et al 2022
“Results of a 5-Year n-Of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment”, Hanley et al 2021
Results of a 5-Year n-of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment
“A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues”, Saul et al 2021
A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
“Senolytic Vaccination Improves Normal and Pathological Age-Related Phenotypes and Increases Lifespan in Progeroid Mice”, Suda et al 2021
“The Flavonoid Procyanidin C1 Has Senotherapeutic Activity and Increases Lifespan in Mice”, Xu et al 2021
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice
“The Metabolic Roots of Senescence: Mechanisms and Opportunities for Intervention”, Wiley & Campisi 2021
The metabolic roots of senescence: mechanisms and opportunities for intervention
“Strategies for Targeting Senescent Cells in Human Disease”, Gasek et al 2021
“Fisetin for COVID-19 in Skilled Nursing Facilities: Senolytic Trials in the COVID Era”, Verdoorn et al 2021
Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era
“Senolytics and the Compression of Late-Life Mortality”, Kowald & Kirkwood 2021
“Procyanidin C1 Is a Natural Agent With Senolytic Activity against Aging and Age-Related Diseases”, Xu et al 2021
Procyanidin C1 is a natural agent with senolytic activity against aging and age-related diseases
“Oxylipin Biosynthesis Reinforces Cellular Senescence and Allows Detection of Senolysis”, Wiley et al 2021
Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis
“The Quest to Slow Ageing through Drug Discovery”, Partridge et al 2020
“Senolytic Drugs: from Discovery to Translation”, Kirkland & Tchkonia 2020
“A Look Back at 2019: Progress Towards the Treatment of Aging As a Medical Condition”, Reason 2019
A Look Back at 2019: Progress Towards the Treatment of Aging as a Medical Condition
“Metformin and Aging: A Review”, Glossmann & Lutz 2019
“Senolytic Treatment Targets Aberrant P21-Expression to Restore Liver Regeneration in Adult Mice”, Ritschka et al 2019
Senolytic treatment targets aberrant p21-expression to restore liver regeneration in adult mice
“Galactose-Modified Duocarmycin Prodrugs As Senolytics”, Guerrero et al 2019
“Senolytics Improve Physical Function and Increase Lifespan in Old Age”, Xu et al 2018
Senolytics improve physical function and increase lifespan in old age:
View PDF:
“The Clinical Potential of Senolytic Drugs”, Kirkland et al 2017
“Targeting Cellular Senescence Prevents Age-Related Bone Loss in Mice”, Farr et al 2017
Targeting cellular senescence prevents age-related bone loss in mice
“Naturally Occurring P16(Ink4a)-Positive Cells Shorten Healthy Lifespan”, Baker et al 2016
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan
“The First Non-Invasive Biomarker to Track and Verify Efficacy of Senolytic Drugs”
The first non-invasive biomarker to track and verify efficacy of senolytic drugs:
“How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Chemotherapeutic Senolytic Drug Candidates”
“Thoughts on Attending RAADfest 2018 in San Diego”
“Overhyping the Effects of Hyperbaric Oxygen Treatment on Aging”
Overhyping the Effects of Hyperbaric Oxygen Treatment on Aging
“A Senolytic Treatment Improves Visual Function in a Small Trial for Macular Degeneration”
A Senolytic Treatment Improves Visual Function in a Small Trial for Macular Degeneration
“Peter De Keizer on Senolytics”
“Reversal of Lung Fibrosis in Mouse Model Suggests a Novel Therapeutic Target for Pulmonary Fibrosis”
Reversal of lung fibrosis in mouse model suggests a novel therapeutic target for pulmonary fibrosis:
Sort By Magic
Annotations sorted by machine learning into inferred 'tags'. This provides an alternative way to browse: instead of by date order, one can browse in topic order. The 'sorted' list has been automatically clustered into multiple sections & auto-labeled for easier browsing.
Beginning with the newest annotation, it uses the embedding of each annotation to attempt to create a list of nearest-neighbor annotations, creating a progression of topics. For more details, see the link.
anti-aging
cell-senescence
procyanidin
senolytic-research
Wikipedia
Miscellaneous
-
https://clinicaltrials.gov/search?term=dasatinib%20quercetin -
https://www.fightaging.org/archives/2023/07/sens-research-foundation-2023-annual-report/ -
https://www.frontiersin.org/articles/10.3389/fnagi.2021.646924/full -
https://www.jhep-reports.eu/article/S2589-5559(21)00077-X/fulltext: -
https://www.longevity.technology/senescence-field-has-completely-exploded/: -
https://www.mdpi.com/2073-4409/10/7/1740/htm:View page:
-
https://www.mdpi.com/2075-1729/11/2/153/htm:View page:
-
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(18)30373-6/fulltext: -
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(18)30629-7/fulltext: -
https://www.wired.com/story/a-hair-loss-study-raises-new-questions-about-aging-cells/:
Bibliography
-
https://www.nature.com/articles/s41467-022-32552-1: “SenMayo: A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways across Tissues”, -
2021-hanley.pdf: “Results of a 5-Year n-Of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment”, -
2021-suda.pdf: “Senolytic Vaccination Improves Normal and Pathological Age-Related Phenotypes and Increases Lifespan in Progeroid Mice”,