Psychiatric diagnoses in childhood
ICD-10 codes: F80-F98
ICD-8 codes: 2958, 299, 3000, 3003, 3013, 3051, 3055, 3056, 3060, 3061, 3062, 3063, 3065, 3066, 3067, 3069, 307, 308, 310, 315, 3479, 7804, 7815, 7816, 7889, 7960
Neurological diagnoses in childhood
ICD-10 codes: C70-C72, C751, C753, D32-D33, D352, D354, G00-G47, G80-G93, S02, S06, S07, S08
ICD-8 codes: 0360, 0459, 065, 136, 191, 1920, 1921, 1922, 1923, 1929, 1943, 1944, 1991, 2250, 2251, 2252, 2253, 2254, 2259, 2262, 2263, 2530, 2532, 2580, 2750, 2901, 292, 2932, 2934, 2939, 2941, 2948, 2949, 3008, 3031, 3032, 3039, 3051, 3052, 3053, 3055, 3056, 3059, 3062, 3064, 3068, 3069, 3074, 308, 309, 3200, 3201, 3208, 3209, 321, 322, 323, 324, 3301, 3309, 3310, 3311, 3312, 3319, 3320, 3321, 3329, 3331, 3339, 340, 341, 342, 343, 344, 3448, 3450, 3451, 3452, 3453, 3459, 346, 347, 3470, 3479, 3480, 3481, 3482, 3488, 3489, 3499, 350, 351, 354, 355, 356, 357, 358, 373, 3770, 3789, 3929, 431, 432, 433, 435, 436, 4369, 437, 4389, 447, 4580, 4829, 573, 596, 7149, 7172, 7289, 729, 7339, 738, 7438, 7439, 7803, 7804, 7805, 7806, 7816, 7817, 7832, 7871, 791, 794, 7960, 800, 801, 8020, 8021, 8022, 8023, 8024, 8025, 803, 804, 8500, 8510, 8511, 8520, 8521, 8530, 8531, 8540, 8541, 8720, 8721, 8730, 8731, 8732, 8733, 8737, 8738, 920, 9673, 9679, 9760, 9909, 9953, 9970, 9989, 9991, 9999
Perinatal diagnoses and congenital deformities
ICD-10 codes: P00-P61, P90-P96, Q00-Q07, Q20-Q28, Q85-Q89
ICD-8 codes: 0039, 011, 0122, 0270, 0389, 0399, 043, 054, 056, 070, 0780, 0795, 0849, 0909, 112, 1301, 136, 208, 2119, 216, 224, 228, 2699, 280, 2871, 288, 2894, 2899, 3302, 344, 3479, 3489, 350, 356, 357, 360, 368, 425, 470, 486, 5112, 5511, 599, 6110, 6259, 6266, 6269, 6821, 6861, 6869, 703, 7330, 7331, 740, 7410, 7419, 742, 7430, 7431, 7432, 7433, 7434, 7438, 7439, 7442, 7459, 7460, 7461, 7462, 7363, 7464, 7465, 7466, 7468, 7469, 7470, 7471, 7472, 7473, 7474, 7475, 7476, 7478, 7479, 7520, 7527, 7533, 7555, 7560, 7568, 7569, 7572, 7579, 7580, 7581, 7582, 7583, 7588, 7589, 7590, 7591, 7592, 7593, 7594, 7595, 7596, 7598, 7599, 7600, 7601, 7602, 7603, 7604, 7605, 7607, 7610, 7612, 7613, 7614, 7615, 7616, 7617, 7619, 7620, 7621, 7622, 7623, 7624, 7625, 7629, 7630, 7631, 7639, 764, 765, 766, 767, 768, 7690, 7691, 7692, 7693, 7694, 7695, 7699, 7700, 7701, 7702, 7708, 7709, 7710, 7711, 7719, 7720, 7721, 7722, 7729, 773, 7740, 7741, 7742, 7749, 7750, 7751, 7752, 7759, 7760, 7761, 7762, 7763, 7764, 7769, 777, 7780, 7781, 7782, 7789, 7790, 7799, 7802, 7824, 7841, 7901, 9602, 9990, 9998
Supplementary Table 1. Associations of IQ score with educational and occupational achievement.
|
Cohort |
|
Within sibship |
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|
b (SE) |
p value |
|
b (SE) |
p value |
||||
Unadjusted associations |
|
||||||||
|
|||||||||
IQ |
0.128 (0.001) |
|
|
0.093 (0.001) |
|
||||
IQ2 |
-3.55x10-5 (1.99x10-5) |
|
|
-8.82x10-5 (2.73x10-5) |
|
||||
IQ3 |
-1.87x10-5 (8.13x10-7) |
<0.001 |
|
-1.54x10-5 (9.71x10-7) |
<0.001 |
||||
Social benefits at ages 18-30 (N=108,855 → 52,211 sibships) |
|
|
|||||||
IQ |
-0.027 (0.001) |
|
|
-0.014 (0.001) |
<0.001 |
||||
IQ2 |
1.42x10-4 (3.04x10-5) |
<0.001 |
|
- |
|
||||
Log of gross income at age 30 (N=228,817 → 108,552 sibships) |
|
||||||||
IQ |
0.003 (1.67x10-4) |
|
|
0.003 (2.74x10-4) |
|
||||
IQ2 |
-8.64x10-5 (9.54x10-6) |
<0.001 |
|
-5.56x10-5 (1.27x10-5) |
<0.001 |
||||
Adjusted associations* |
|
||||||||
GPA in lower secondary school (N=93,458 → 44,677 sibships) |
|
||||||||
IQ |
0.118 (0.001) |
|
|
0.094 (0.001) |
|
||||
IQ2 |
-4.58x10-5 (1.95x10-5) |
|
|
-8.05x10-5 (2.72x10-5) |
|
||||
IQ3 |
-1.78x10-5 (7.90x10-7) |
<0.001 |
|
-1.58x10-5 (9.69x10-7) |
<0.001 |
||||
Social benefits at ages 18-30 (N=108,855 → 52,211 sibships) |
|
|
|||||||
IQ |
-0.017 (0.001) |
|
|
-0.011 (0.001) |
<0.001 |
||||
IQ2 |
1.00x10-4 (3.13x10-5) |
0.001 |
|
- |
|
||||
Log of gross income at age 30 (N=228,817 → 108,552 sibships) |
|
||||||||
IQ |
0.002 (1.97x10-4) |
|
|
0.002 (3.18x10-4) |
|
||||
IQ2 |
-3.63x10-5 (1.08x10-5) |
0.001 |
|
-4.23x10-5 (1.30x10-5) |
0.001 |
||||
*Adjusted for year of birth, ethnicity, birth region, parental education at birth, out-of-home care in childhood, psychiatric diagnoses in childhood, neurological diagnoses in childhood, and perinatal diagnoses and congenital deformities.
IQ indicates a linear IQ term, IQ2 indicates a quadratic IQ term, and IQ3 indicates a cubic IQ term.
Missing values have been imputed by use of multiple imputation.
Supplementary Figure 1. Grade point average according to IQ.
Association is adjusted for year of birth, ethnicity, birth region, parental education at birth, out-of-home care in childhood, psychiatric diagnoses in childhood, neurological diagnoses in childhood, and perinatal diagnoses and congenital deformities.
Supplementary Figure 2. Hazard ratio for social benefits according to IQ.
Association is adjusted for year of birth, ethnicity, birth region, parental education at birth, out-of-home care in childhood, psychiatric diagnoses in childhood, neurological diagnoses in childhood, and perinatal diagnoses and congenital deformities.
Supplementary Figure 3. Gross income according to IQ.
Association is adjusted for year of birth, ethnicity, birth region, parental education at birth, out-of-home care in childhood, psychiatric diagnoses in childhood, neurological diagnoses in childhood, and perinatal diagnoses and congenital deformities.
Supplementary Table 2. Associations of IQ score with educational and occupational achievement.
|
Cohort |
|
Excluded individuals |
||||||
|
b (SE) |
p value |
|
b (SE) |
p value |
||||
GPA in lower secondary school (N=93,458/N=207,090) |
|
||||||||
IQ |
0.118 (0.001) |
|
|
0.117 (4.81x10-4) |
|
||||
IQ2 |
-4.58x10-5 (1.95x10-5) |
|
|
-7.07x10-5 (1.34x10-5) |
|
||||
IQ3 |
-1.78x10-5 (7.90x10-7) |
<0.001 |
|
-1.77x10-5 (6.16x10-7) |
<0.001 |
||||
Social benefits at ages 18-30 (N=108,855/N=251,381) |
|
|
|||||||
IQ |
-0.017 (0.001) |
|
|
-0.017 (4.37x10-4) |
|
||||
IQ2 |
1.00x10-4 (3.13x10-5) |
0.001 |
|
4.95x10-5 (2.16x10-5) |
0.02 |
||||
Log of gross income at age 30 (N=228,817/N=571,596) |
|
||||||||
IQ |
0.002 (1.97x10-4) |
|
|
0.003 (1.34x10-4) |
|
||||
IQ2 |
-3.63x10-5 (1.08x10-5) |
0.001 |
|
-3.52x10-5 (5.83x10-6) |
<0.001 |
||||
Associations are adjusted for year of birth, ethnicity, birth region, parental education at birth, out-of-home care in childhood, psychiatric diagnoses in childhood, neurological diagnoses in childhood, and perinatal diagnoses and congenital deformities.
IQ indicates a linear IQ term, IQ2 indicates a quadratic IQ term, and IQ3 indicates a cubic IQ term.
Missing values have been imputed by use of multiple imputation.